HCID 54421298, compound → HCID 19094155, compound

Participants

Reaction Steps

0.14 g of 10% w/w palladium-on-charcoal and 1.569 g of ethyl 3-{1-[2-bis(4-fluorophenyl)methoxyethyl]-4-piperidyl}acrylate (prepared as described in Example 1) were added to 30 ml of ethanol, and the mixture was stirred in an atmosphere of hydrogen at room temperature for 30 minutes. At the end of this time, the catalyst was removed by filtration, and the filtrate was freed from the solvent by distillation under reduced pressure, to afford 1.46 g (93% yield) of the title compound as a yellow oil.

Provenance & Evidence