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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 487341Generated: October 29, 2026

Pyridine → 1-(2-Methoxy-2-oxoethyl)pyridinium chloride

https://huagongshe.com/reaction/487341

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantMethyl chloroacetateHCID 7295—
SolventEthyl AcetateHCID 8857—
Product1-(2-Methoxy-2-oxoethyl)pyridinium chlorideHCID 11769267—

Reaction Steps

Pyridine (1 equivalent) and methyl chloroacetate (1 equivalent) in ethyl acetate were heated (80° C.) for 24 hours. The reaction mixture was cooled to room temperature and the resulting crystalline pyridinium salt filtered, washed with ethyl acetate, and dried in vacuum.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05294721
Source datasetuspto-grants-1994_03
ORD IDord-d6f60419ed23424aa2a11487ac3fbb00
Source noteuspto-grants-1994_03