Pyridine → 1-(2-Methoxy-2-oxoethyl)pyridinium chloride

HRID 487341Notes

Reaction equation

HRID 487341 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:7][CH2:8][C:9]([O:11][CH3:12])=[O:10]>C(OCC)(=O)C>[Cl-:7].[CH3:12][O:11][C:9]([CH2:8][N+:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:10]

Participants

4

Reactant 2

HCID 1049PyridineHCID 7295Methyl chloroacetate

Product 1

HCID 117692671-(2-Methoxy-2-oxoethyl)pyridinium chloride

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Pyridine (1 equivalent) and methyl chloroacetate (1 equivalent) in ethyl acetate were heated (80° C.) for 24 hours. The reaction mixture was cooled to room temperature and the resulting crystalline pyridinium salt filtered, washed with ethyl acetate, and dried in vacuum.

Workup

  1. filtrationthe resulting crystalline pyridinium salt filtered
  2. washwashed with ethyl acetate
  3. customdried in vacuum

Sources & evidence

ORD record
ord-d6f60419ed23424aa2a11487ac3fbb00
Source dataset
uspto-grants-1994_03
Patent number
US05294721

Reaction notes

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