Pyridine → 1-(2-Ethoxy-2-oxoethyl)pyridin-1-ium chloride

HRID 487342Notes

Reaction equation

HRID 487342 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:7][CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10]>C(OCC)(=O)C>[Cl-:7].[CH2:12]([O:11][C:9]([CH2:8][N+:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:10])[CH3:13]

Participants

4

Reactant 2

HCID 1049PyridineHCID 7751Ethyl chloroacetate

Product 1

HCID 111381401-(2-Ethoxy-2-oxoethyl)pyridin-1-ium chloride

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Pyridine (1 equivalent) and ethyl chloroacetate (1 equivalent) in ethyl acetate were heated (70° C.) for 24 hours. The reaction mixture was cooled to room temperature and the resulting crystalline pyridinium salt filtered, washed with ethyl acetate, and dried in vacuum.

Workup

  1. filtrationthe resulting crystalline pyridinium salt filtered
  2. washwashed with ethyl acetate
  3. customdried in vacuum

Sources & evidence

ORD record
ord-b15aed9988544fb3aa12a2a2f218286b
Source dataset
uspto-grants-1994_03
Patent number
US05294721

Reaction notes

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