7-Bromoquinolin-2(1H)-one → 7-Bromo-6-(4-hydroxypiperidino)-3,4-dihydrocarbostyril

Participants

Reaction Steps

This 7-bromocarbostyril was dissolved in 2.5 ml of hydrogen chloride-methanol solution, and mixture was refluxed for 1 hr. The reaction mixture was concentrated and purified by a silica gel column chromatography to give 56 mg of 7-bromo-6-(4-hydroxypiperidino)-3,4-dihydrocarbostyril.

Provenance & Evidence