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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 487431Generated: October 30, 2026

(S)-4-Glycyl-3-(1-methylpropyl)-2-oxopiperazine-1-acetic acid t-butyl ester hydrochloride → HCID 178445837, compound

https://huagongshe.com/reaction/487431

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-4-Glycyl-3-(1-methylpropyl)-2-oxopiperazine-1-acetic acid t-butyl ester hydrochlorideHCID 70046267—
ReactantHCID 178479383HCID 178479383—
ProductHCID 178445837HCID 178445837—

Reaction Steps

(S)-4-Glycyl-3-(1-methylpropyl)-2-oxopiperazine-1-acetic acid t-butyl ester hydrochloride obtained in Working Example 64 (364 mg) and 215 mg of 4-guanidino benzoic acid hydrochloride were subjected to substantially the same procedure as in Working Example 39 to afford 190 mg of the title compound as colorless powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05294713
Source datasetuspto-grants-1994_03
ORD IDord-419a1e360fa3485d949b0cd687b783a6
Source noteuspto-grants-1994_03