Methanol → HCID 19014038, compound

Participants

Reaction Steps

Potassium acetate (8.2 g) was added to a mixture of ethyl 4-methanesulfonamidobenzoylacetate (23.0 g), hydroxylamine hydrochloride (5.8 g) and methanol (35 ml), and the mixture was heated for refluxing for 30 minutes. The reaction mixture was poured into water (210 ml) to filter off the deposited crystals and dry them, whereby 3-(4-methanesulfonamidophenyl)isoxazoline-5-one (11.3 g) was obtained.

Provenance & Evidence