HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(3-Thienyl)propionic acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-(Thiophen-3-yl)propanoic acid | HCID 13134867 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-(3-Thienyl)propionic acid chloride | HCID 21834152 | — |
Reaction Steps
The 2-(3-thienyl)propionic acid (22.9 g) was dissolved in chloroform (60 ml), to which was added thionyl chloride (20 g), followed by 30 minutes refluxing. The reaction was carried out in a similar manner to the foregoing Example 9 to obtain 2-(3-thienyl)propionic acid chloride with bp 76°-78° C./2.0 torr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05296454 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-38c575b82ab44d9ab1beab35d1ac6ef0 |
| Source note | uspto-grants-1994_03 |