Potassium Iodide → HCID 19092180, compound

HRID 487537Notes

Reaction equation

HRID 487537 reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[C:15]2[N:19]([C:20]([C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[N:18]=[N:17][N:16]=2)=[CH:5][CH:4]=1.[I-:39].[K+]>CC(C)=O>[I:39][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[C:15]2[N:19]([C:20]([C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[N:18]=[N:17][N:16]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 4875Potassium IodideHCID 100534615-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetraazole

Product 1

HCID 19092180HCID 19092180, compoundYield 94.5%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 4.0 g of 5-[4'-(bromomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-1H-tetrazole and 2.2 g of potassium iodide in 50 ml of acetone is heated at reflux for 50 minutes. The reaction mixture is filtered and the filtrate evaporated in vacuo to a residue which is stirred with cold water and the resulting solid collected by filtration, washed with water and air dried to give 4.1 g of the desired product as a solid.

Workup

  1. temperatureis heated
  2. temperatureat reflux for 50 minutes
  3. filtrationThe reaction mixture is filtered
  4. customthe filtrate evaporated in vacuo to a residue which
  5. filtrationthe resulting solid collected by filtration
  6. washwashed with water and air
  7. customdried

Sources & evidence

ORD record
ord-5f76242733484dd2be7057bf235c2cf2
Source dataset
uspto-grants-1994_03
Patent number
US05296480

Reaction notes

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