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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 487574Generated: October 28, 2026

4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine → 4-(4-Fluorophenyl)-1-[1-(4-nitrophenyl)-4-piperidinyl]-1,2,5,6-tetrahydropyridine

https://huagongshe.com/reaction/487574

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridineHCID 197748—
Reactant1-(4-Nitrophenyl)piperidin-4-oneHCID 3842562—
Product4-(4-Fluorophenyl)-1-[1-(4-nitrophenyl)-4-piperidinyl]-1,2,5,6-tetrahydropyridineHCID 19092272—

Reaction Steps

5.5 g of 1-(4-nitrophenyl)-4-piperidone and 4.4 g of 4-(4-fluorophenyl)-1,2,5,6-tetrahydropyridine were reacted as in Example 1. The product crystallized as fumarate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05296485
Source datasetuspto-grants-1994_03
ORD IDord-ecfc00dc6c264b1a84ff89904ceef1b1
Source noteuspto-grants-1994_03