反应详情

A mixture of 2-phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde (0.5 g) and hydroxylamine hydrochloride (0.17 g) in ethanol (5 ml) was refluxed for 1.5 hours and evaporated in vacuo. The residue was triturated with ethyl acetate and recrystallized from a mixture of ethanol and ethyl acetate to give 2-phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde oxime hydrochloride (0.28 g).

1. temperaturewas refluxed for 1.5 hours
2. customevaporated in vacuo
3. customThe residue was triturated with ethyl acetate
4. customrecrystallized from a mixture of ethanol and ethyl acetate