HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Chloro-2-methoxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Chloro-o-anisic acid | HCID 93682 | — |
| Product | 4-Chloro-2-methoxybenzoyl chloride | HCID 22142450 | — |
Reaction Steps
120 ml of thionyl chloride was dropwise added at room temperature to 75 g of 4-chloro-2-anisic acid, and the mixture was stirred at room temperature for 12 hr. The reaction mixture was concentrated for crystallization. The crystal was used for the subsequent reaction without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05298518 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-f1053cecc089414eb6eb9c52d3d61ee5 |
| Source note | uspto-grants-1994_03 |