Hydrochloric Acid → HCID 178454908, compound

HRID 488185Notes

Reaction equation

HRID 488185 reaction equation
[CH2:1]([O:3][CH:4]([PH:8](=[O:12])OCC)[O:5][CH2:6][CH3:7])[CH3:2].[CH2:13]([Li])[CH2:14][CH2:15][CH3:16].Cl>CCCCCC>[CH2:13]([PH:8](=[O:12])[CH:4]([O:3][CH2:1][CH3:2])[O:5][CH2:6][CH3:7])[CH2:14][CH2:15][CH3:16]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 178418339ButyllithiumHCID 178472284HCID 178472284, compound

Product 1

HCID 178454908HCID 178454908, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Following the procedure of Example 8, but using 1.96 g of ethyl diethoxymethylphosphinate and 12.5 ml of a 1.6 molar solution of n-butyl lithium in n-hexane and adding 20 ml of 0.1M hydrochloric acid prior to extraction, n-butyl(diethoxymethyl) phosphine oxide is obtained as a colourless oil.

Workup

  1. extractionto extraction

Sources & evidence

ORD record
ord-2277432bade34b168962db8a9fb747e3
Source dataset
uspto-grants-1994_03
Patent number
US05298663

Reaction notes

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