Methyl bromoacetate → [2-[(Pyridin-2-yl-methyl)-carbamoyl-methyl]-1-(3,4-dimethoxy-benzyl)-8-methoxy-1,2,3,4-tetrahydro-isoquinolin-5-yloxy]-acetic acid methyl ester

Participants

Role	Name	HCID	Charge
Reactant	Methyl bromoacetate	HCID 60984	—
Reactant	2-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide	HCID 22742553	—
Product	[2-[(Pyridin-2-yl-methyl)-carbamoyl-methyl]-1-(3,4-dimethoxy-benzyl)-8-methoxy-1,2,3,4-tetrahydro-isoquinolin-5-yloxy]-acetic acid methyl ester	HCID 69895401	—

Reaction Steps

prepared by reaction of 2-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide with methyl bromoacetate

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06703392B2
Source dataset	uspto-grants-2004_03
ORD ID	ord-2425a704e4e94df3b6a868c72b65deab
Source note	uspto-grants-2004_03