Sodium Hydroxide → N-(carboxymethyl)-N-[3-(tetradecyloxy)benzoyl]glycine

HRID 488249Notes

Reaction equation

HRID 488249 reaction equation
[OH-].[Na+].C[O:4][C:5](=[O:36])[CH2:6][N:7]([CH2:31][C:32]([O:34]C)=[O:33])[C:8](=[O:30])[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH:10]=1>>[C:5]([CH2:6][N:7]([C:8](=[O:30])[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH:10]=1)[CH2:31][C:32]([OH:34])=[O:33])([OH:36])=[O:4]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 19091823N-(2-methoxy-2-oxoethyl)-N-[3-(tetradecyloxy)benzoyl]glycine methyl ester

Product 1

HCID 19091841N-(carboxymethyl)-N-[3-(tetradecyloxy)benzoyl]glycine

Procedure

Sodium hydroxide hydrolysis of N-(2-methoxy-2-oxoethyl)-N-[3-(tetradecyloxy)benzoyl]glycine methyl ester as in Example 4 gave N-(carboxymethyl)-N-[3-(tetradecyloxy)benzoyl]glycine, mp 96°-99°.

Sources & evidence

ORD record
ord-bf6a63aaaa2840499e25702fc1942076
Source dataset
uspto-grants-1994_03
Patent number
US05298652

Reaction notes

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