HRID488269

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24386

Thionyl chloride

Cl2OS

HCID428827

未命名化合物

结构：CCCCCCCCCCCCCCCCCCOc1cc(OCc2ccccc2)cc(C(=O)O)c1

HCID19389046

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCCOc1cc(OCc2ccccc2)cc(C(=O)N(CC(=O)OC)CC(=O)OC)c1

HCID19091826

未命名化合物

PROCEDURE

实验过程

Conversion of 3-(octadecyloxy)-5-(phenylmethoxy)benzoic acid to the acid chloride with thionyl chloride followed by treatment with dimethyl iminodiacetate gave N-(2-methoxy-2-oxoethyl)-N-[3-(octadecyloxy)-5-(phenylmethoxy)benzoyl]glycine methyl ester as an oil after chromatography on 50 g of silica gel using 25% ethyl acetate-hexane. The structure was confirmed by the nmr spectrum.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a640b00347b44a50a9d126925ce2722f
来源数据集: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05298652
来源说明: uspto-grants-1994_03

反应 SMILES

[CH2:1]([O:19][C:20]1[CH:21]=[C:22]([CH:26]=[C:27]([O:29][CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:28]=1)[C:23]([OH:25])=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].S(Cl)(Cl)=O.[NH:41]([CH2:47][C:48]([O:50][CH3:51])=[O:49])[CH2:42][C:43]([O:45][CH3:46])=[O:44]>>[CH3:51][O:50][C:48](=[O:49])[CH2:47][N:41]([CH2:42][C:43]([O:45][CH3:46])=[O:44])[C:23](=[O:25])[C:22]1[CH:26]=[C:27]([O:29][CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:28]=[C:20]([O:19][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH:21]=1