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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488316Generated: October 30, 2026

Sodium Hydroxide → N-(carboxymethyl)-N-[5-(decyloxy)-2-(phenylmethoxy)benzoyl]glycine

https://huagongshe.com/reaction/488316

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantN-(2-ethoxy-2-oxoethyl)-N-[5-(decyloxy)-2-(phenylmethoxy)benzoyl]glycine ethyl esterHCID 19091876—
ProductN-(carboxymethyl)-N-[5-(decyloxy)-2-(phenylmethoxy)benzoyl]glycineHCID 1909177694%

Reaction Steps

Sodium hydroxide hydrolysis of N-(2-ethoxy-2-oxoethyl)-N-[5-(decyloxy)-2-(phenylmethoxy)benzoyl]glycine ethyl ester under conditions described in Example 81 gave N-(carboxymethyl)-N-[5-(decyloxy)-2-(phenylmethoxy)benzoyl]glycine (94% yield, mp 74°-78°).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05298652
Source datasetuspto-grants-1994_03
ORD IDord-9e16c53460e647da80258ffb231ab7f3
Source noteuspto-grants-1994_03