HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 19091856, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-(2-ethoxy-2-oxoethyl)-N-[5-[[6-([1,1'-biphenyl]-4-yloxy)hexyl]oxy]-2-(phenylmethoxy) benzoyl]glycine ethyl ester | HCID 19091786 | — |
| Product | HCID 19091856 | HCID 19091856 | 82% |
Reaction Steps
Sodium hydroxide hydrolysis of N-(2-ethoxy-2-oxoethyl)-N-[5-[[6-([1,1'-biphenyl]-4-yloxy)hexyl]oxy]-2-(phenylmethoxy)benzoyl]glycine ethyl ester under conditions described in Example 81 gave N-[5-[[6-([1,1'-biphenyl]-4-yloxy)hexyl]oxy]-2(phenylmethoxy)benzoyl]-N-(carboxymethyl)glycine (82% yield, mp 98°-100° ).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05298652 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-fd2273131079485e8f25b98abd290c58 |
| Source note | uspto-grants-1994_03 |