HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl iminodiacetate → N-(2-ethoxy-2-oxoethyl)-N-[5-[(12-phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoyl]glycine ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl iminodiacetate | HCID 80502 | — |
| Reactant | 5-[(12-Phenoxydodecyl)oxy]-2-(phenylmethoxy) benzoic acid chloride | HCID 54160397 | — |
| Product | N-(2-ethoxy-2-oxoethyl)-N-[5-[(12-phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoyl]glycine ethyl ester | HCID 19091873 | 56% |
Reaction Steps
The reaction of 5-[(12-phenoxydodecyl)oxy]-2-(phenylmethoxy) benzoic acid chloride with diethyl iminodiacetate under conditions described in Example 80 gave N-(2-ethoxy-2-oxoethyl)-N-[5-[(12-phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoyl]glycine ethyl ester (56% yield, mp 49°-50° ). The structure was confirmed by nmr and mass spectra.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05298652 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-becde61c4bb64533b1e0a9076d398588 |
| Source note | uspto-grants-1994_03 |