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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488493Generated: October 30, 2026

(4-Nitrophenyl)acetic acid → HCID 54348404, compound

https://huagongshe.com/reaction/488493

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactant3,4,5-TrimethoxybenzaldehydeHCID 6858—
ReactantPiperidineHCID 8082—
ProductHCID 54348404HCID 5434840441%

Reaction Steps

The title compound was prepared from p-nitrophenylacetic acid (18.6 g, 0.10 mol), 3,4,5-trimethoxy-benzaldehyde (19.6 g, 0.10 mol) and piperidine (5 mL) using the procedure described in Example 1, Step A. This procedure yielded a solid, 13.0 g (0.041 mol, 41%) of the desired product. mp: 192-195° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06972287B1
Source datasetuspto-grants-2005_12
ORD IDord-44781a1ff86b4f95844bd7c455d1a75c
Source noteuspto-grants-2005_12