Boron tribromide → HCID 22269771, compound

HRID 488496Notes

Reaction equation

HRID 488496 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][C:18]([NH:21][C:22]3[CH:30]=[CH:29][CH:28]=[CH:27][C:23]=3[C:24]([OH:26])=[O:25])=[CH:17][CH:16]=2)[CH:6]=[C:7]([O:11]C)[C:8]=1[O:9]C.B(Br)(Br)Br>C(Cl)Cl>[OH:2][C:3]1[CH:4]=[C:5]([CH2:13][CH2:14][C:15]2[CH:16]=[CH:17][C:18]([NH:21][C:22]3[CH:30]=[CH:29][CH:28]=[CH:27][C:23]=3[C:24]([OH:26])=[O:25])=[CH:19][CH:20]=2)[CH:6]=[C:7]([OH:11])[C:8]=1[OH:9]

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 22269716HCID 22269716, compound

Product 1

HCID 22269771HCID 22269771, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared from 2-{4-[2-(3,4,5-trimethoxy-phenyl)-ethyl]phenylamino}benzoic acid (0.50 g, 1.23 mmol) in CH2Cl2 (40 mL) and BBr3 (10 mL, 1M in CH2Cl2, 10.0 mmol) using the procedure described in Example 4, Step D. This procedure yielded a green solid, 0.25 g (0.68 mmol, 65%) of the desired product. mp: 160.0-162.0° C.

Sources & evidence

ORD record
ord-4ff8754eefc44385a036d83e6d4a0da2
Source dataset
uspto-grants-2005_12
Patent number
US06972287B1

Reaction notes

Loading…