HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-{4-[3-(3,4-Dichlorophenyl)propyl]phenylamino}-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-{4-[3-(3,4-Dichlorophenyl)-propyl]phenylamino}benzoic acid methyl ester | HCID 54513625 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-{4-[3-(3,4-Dichlorophenyl)propyl]phenylamino}-benzoic acid | HCID 10111576 | 81% |
Reaction Steps
The title compound was prepared from 2-{4-[3-(3,4-dichlorophenyl)-propyl]phenylamino}benzoic acid methyl ester (0.41 g, 0.99 mmol), 1N NaOH (4.0 mL) in EtOH (4 mL) and THF (4 mL) using the procedure described in Example 2. This procedure yielded a yellow solid, 0.32 g (0.80 mmol, 81%) of the desired product mp 120-126° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06972287B1 |
| Source dataset | uspto-grants-2005_12 |
| ORD ID | ord-b5ba8dcfe4ec4395b3a9d8e8c14c9569 |
| Source note | uspto-grants-2005_12 |