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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488514Generated: October 31, 2026

Sodium Hydroxide → HCID 22269687, compound

https://huagongshe.com/reaction/488514

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 53955704HCID 53955704—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22269687HCID 22269687100.9%

Reaction Steps

The title compound was 2-{4-[3-(3,4-dichlorophenyl)-propyl]phenylamino}-5-nitrobenzoic acid methyl ester (0.50 g, 1.09 mmol), 2N NaOH (5.0 mL) in EtOH (2 mL) and THF (4 mL) using the procedure described in Example 2. This procedure yielded an orange solid, 0.49 g (1.10 mmol, 100%) of the desired product. mp 153-155° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06972287B1
Source datasetuspto-grants-2005_12
ORD IDord-ddf2572f584a4a7ab60789eb88b2a061
Source noteuspto-grants-2005_12