反应详情

4-(2-Chlorophenyl)-5-cyano-6-dimethoxymethyl-4,7-dihydro-2H-pyrazolo[3,4-b]pyridine (4.4 g) was added to trifluoroacetic acid (20 ml) under ice-cooling and the mixture was stirred at room temperature for 2.5 hours. The reaction mixture was concentrated under reduced pressure and crystallized from ethyl acetate (50 ml) to give the title compound (1.9 g) as yellow crystals.

1. temperaturecooling
2. concentrationThe reaction mixture was concentrated under reduced pressure
3. customcrystallized from ethyl acetate (50 ml)