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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 489433Generated: October 30, 2026

Piperidine → 4-(2-chlorophenyl)-6-(piperidin-1-ylmethyl)-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile;hydrochloride

https://huagongshe.com/reaction/489433

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
ReactantHCID 178509439HCID 178509439—
Product4-(2-chlorophenyl)-6-(piperidin-1-ylmethyl)-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile;hydrochlorideHCID 178479185—

Reaction Steps

The title compound was prepared from 4-(2-chlorophenyl)-5-cyano-6-bromomethyl-4,7-dihydro-2H-pyrazolo[3,4-b]pyridine and piperidine in the same manner as in Example 352.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06977262B2
Source datasetuspto-grants-2005_12
ORD IDord-eafa32cb14e3457f93ea1eb7b9f27fbb
Source noteuspto-grants-2005_12