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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 489455Generated: October 29, 2026

1-Phenylpiperazine → 4-(2-chlorophenyl)-6-[(4-phenylpiperazin-1-yl)methyl]-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile;trihydrochloride

https://huagongshe.com/reaction/489455

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PhenylpiperazineHCID 7096—
ReactantHCID 178509439HCID 178509439—
Product4-(2-chlorophenyl)-6-[(4-phenylpiperazin-1-yl)methyl]-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile;trihydrochlorideHCID 178478585—

Reaction Steps

The title compound was prepared from 4-(2-chlorophenyl)-5-cyano-6-bromomethyl-4,7-dihydro-2H-pyrazolo[3,4-b]pyridine and 1-phenylpiperazine in the same manner as in Example 1076.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06977262B2
Source datasetuspto-grants-2005_12
ORD IDord-9cefe22d687b41d99bc6fbde3da4cc6a
Source noteuspto-grants-2005_12