反应详情

0.71 g of 2-chloro-4-fluorophenol, 0.77 g of 3-allyl-5-chloromethyl-1,2,4-oxadiazole and 0.83 of potassium carbonate were added to 20 ml of acetone. After completion of the reaction, the resulting precipitates were filtered out from the mixture and then acetone was removed by distillation, and the residue was purified by column chromatography (benzene:hexane=1:1) to obtain 1.05 g of the desired product(yield: 80.8%).

1. customAfter completion of the reaction
2. customthe resulting precipitates
3. filtrationwere filtered out from the mixture
4. customacetone was removed by distillation
5. customthe residue was purified by column chromatography (benzene:hexane=1:1)