反应详情

A reaction mixture obtained by adding 20 g of 4-cyano-4′-hydroxybiphenyl, 20 g of ally bromide and 25 g of potassium carbonate to 250 mL of butanone was refluxed for 7 hours. Water was added to the reaction mixture, which was then separated. An organic layer was washed with water and dried over anhydrous magnesium sulfate. The solvent was distilled off to obtain a residue, which was purified by silica gel column chromatography using toluene as an elusion solvent and then subjected to recrystallization from ethanol to obtain 22 g of 4-allyloxy-4′-cyanobiphenyl.

1. customA reaction mixture obtained
2. temperaturewas refluxed for 7 hours
3. customwas then separated
4. washAn organic layer was washed with water
5. dry with materialdried over anhydrous magnesium sulfate
6. distillationThe solvent was distilled off
7. customto obtain a residue, which
8. customwas purified by silica gel column chromatography
9. customsubjected to recrystallization from ethanol