HCID 43384283, compound → HCID 43384268, compound

HRID 490079Notes

Reaction equation

HRID 490079 reaction equation
C1(N2CCN(C3C(N)=CC=CN=3)CC2)CCCC1.[CH:19]1([N:24]2[CH2:29][CH2:28][N:27]([C:30]3[CH:35]=[CH:34][C:33]([N+:36]([O-])=O)=[CH:32][N:31]=3)[CH2:26][CH2:25]2)[CH2:23][CH2:22][CH2:21][CH2:20]1>>[CH:19]1([N:24]2[CH2:25][CH2:26][N:27]([C:30]3[N:31]=[CH:32][C:33]([NH2:36])=[CH:34][CH:35]=3)[CH2:28][CH2:29]2)[CH2:20][CH2:21][CH2:22][CH2:23]1

Participants

3

Reactant 2

HCID 43384283HCID 43384283, compoundHCID 47159344HCID 47159344, compound

Product 1

HCID 43384268HCID 43384268, compoundYield 98%

Procedure

According to the procedure described for the synthesis of intermediate 2-(4-cyclopentyl-piperazin-1-yl)-pyridin-3-ylamine was synthesized from 1-cyclopentyl-4-(5-nitro-pyridin-2-yl)-piperazine through hydrogenation to yield 98% of the title compound as colorless crystals. (m/e): 247.1 (MH+; 100%).

Sources & evidence

ORD record
ord-963d811e615e4510adb8770f52379006
Source dataset
uspto-grants-2009_05
Patent number
US07528135B2

Reaction notes

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