HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Isobutyl-4-(5-nitro-pyridin-2-yl)-piperazine → HCID 24253463, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Isobutyl-4-(5-nitro-pyridin-2-yl)-piperazine | HCID 68406877 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 24253463 | HCID 24253463 | 95.1% |
Reaction Steps
A mixture of 2.48 g 1-isobutyl-4-(5-nitro-pyridin-2-yl)-piperazine (intermediate 7) and 0.8 g Pd/C (10%) in 30 ml methanol was treated with 1 bar hydrogen at room temperature for 2 h. After filtration the mixture was evaporated to dryness to yield 2.09 g (95%) of the title compound as colorless solid. (m/e): 235.0 (MH+; 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528135B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-394e269e94d347aa8b0780d144b85564 |
| Source note | uspto-grants-2009_05 |