HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-(N-Boc-amino)piperidine → 4-(N-Boc-amino)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-(N-Boc-amino)piperidine | HCID 4438618 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
Reaction Steps
A solution of D6 (10 g, 3.4 mmol) in methanol (150 ml) was hydrogenated at 50 psi in a Parr hydrogenator using 10% Palladium on carbon catalyst (800 mg) for 18 h. Catalyst was filtered off and the filtrate concentrated under reduced pressure to afford the product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528151B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-791ab8199bb048bbb535676d6d60f300 |
| Source note | uspto-grants-2009_05 |