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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 490303Generated: October 30, 2026

1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-4-amine → HCID 69066579, compound

https://huagongshe.com/reaction/490303

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-4-amineHCID 4778234—
Reactant2-Bromo-4-(trifluoromethyl)-1,3-thiazoleHCID 23149887—
Reactant[(R)-1-(3-Trifluoromethylpyridin-2-yl)pyrrolidin-3-yl]-carbamic acid tert-butyl esterHCID 67001808—
Reactant(R)-1-(3-Trifluoromethylpyridin-2-yl)pyrrolidin-3-ylamineHCID 68801104—
ProductHCID 69066579HCID 69066579—

Reaction Steps

Prepared from D8 and 2-bromo4-trifluoromethylthiazole (J. A. Edwards Ger. Offen., 2252070, 1973) in a manner similar to that described in D1 and D2. The following were prepared using methods described above and in a manner similar to that of D18:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07528151B2
Source datasetuspto-grants-2009_05
ORD IDord-a26077184d90414ea295d68383d97a35
Source noteuspto-grants-2009_05