HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) → 5-Methyl-4-(2'-trifluoromethoxy-biphenyl-4-yloxymethyl)-furan-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) | HCID 2777204 | — |
| Reactant | 4-(4-Iodo-phenoxymethyl)-5-methyl-furan-2-carboxylic acid | HCID 18444654 | — |
| Product | 5-Methyl-4-(2'-trifluoromethoxy-biphenyl-4-yloxymethyl)-furan-2-carboxylic acid | HCID 18444602 | — |
Reaction Steps
Compound (115) was prepared from compound (26) and (2-trifluoromethoxy-phenyl)-boronic acid by adapting the procedure of Example 27B. LC/MS System B; Rt=1.97 mins, m/z (ES−)=391 (M−H for C20H15F3O5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528157B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-20e756d4c4f6456b84e5078f72255a42 |
| Source note | uspto-grants-2009_05 |