HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Carbobenzyloxy-1-(5,6-dichloro-2-nitrophenyl)piperazine-2-carboxylic acid → 3-Carbobenzyloxy-9,10-Dichloro-2,3,4,4a-Tetrahydro-1H-Pyrazino[1,2-a]Quinoxalin-5(6H)-One
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Carbobenzyloxy-1-(5,6-dichloro-2-nitrophenyl)piperazine-2-carboxylic acid | HCID 21976687 | — |
| Catalyst | Iron | HCID 23925 | — |
| Product | 3-Carbobenzyloxy-9,10-Dichloro-2,3,4,4a-Tetrahydro-1H-Pyrazino[1,2-a]Quinoxalin-5(6H)-One | HCID 21976679 | 50.7% |
Reaction Steps
By the same procedure described for Example 7 B, from 0.75 g of 4-carbobenzyloxy-1-(5,6-dichloro-2-nitrophenyl)piperazine-2-carboxylic acid and 0.28 g of iron powder, there was obtained 0.34 g (49%) of the desired product as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06706714B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-1390c26cb3bd43e8aa6540a4f555b7d0 |
| Source note | uspto-grants-2004_03 |