HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorobenzyl chloride → HCID 60295281, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorobenzyl chloride | HCID 7609 | — |
| Reactant | Methyl 4-hydroxypyrrolidine-2-carboxylate | HCID 549381 | — |
| Product | HCID 60295281 | HCID 60295281 | 70% |
Reaction Steps
As described for Example 64a, 4-hydroxy-pyrrolidine-2-carboxylic acid methyl ester (10 mmol) was converted, using 1,2-dichloro-4-chloromethyl-benzene instead of 1-chloro-3-chloromethyl-benzene, to the title compound (2.14 g) in 70% yield as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528136B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-461c0e026cbe44ea8bbcf5fe7848b17c |
| Source note | uspto-grants-2009_05 |