Methylamine → 6-Hydroxy-N-methyl-1-naphthamide

HRID 490849Notes

Reaction equation

HRID 490849 reaction equation

[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([C:12]([OH:14])=O)=[CH:7][CH:6]=[CH:5]2.[CH3:15][NH2:16]>>[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([C:12]([NH:16][CH3:15])=[O:14])=[CH:7][CH:6]=[CH:5]2

Participants

3

Reactant 2

HCID 6329Methylamine

HCID 54638006-Hydroxy-1-naphthoic acid

Product 1

HCID 228927966-Hydroxy-N-methyl-1-naphthamide

Procedure

Prepared from 6-hydroxy-1-naphthoic acid and methylamine using the method of preparation 57 to give the title compound as a pale orange solid.

Workup

customthe method of preparation 57

Sources & evidence

ORD record: ord-ad7c2768ec58402fa3c6a96092351ca6
Source dataset: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07528170B2

Reaction notes

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