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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49108Generated: October 29, 2026

Piperidine → HCID 69436130, compound

https://huagongshe.com/reaction/49108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
ReactantN-methyl-2-oxoindoline-5-sulfonamideHCID 10176909—
Reactant4-methoxy-1H-indole-2-carbaldehydeHCID 10678838—
SolventEthanolHCID 702—
ProductHCID 69436130HCID 69436130—

Reaction Steps

A mixture of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide (194 mg, 0.86 mmol), 4-methoxy-1H-indole-2-carbaldehyde (150 mg, 0.86 mmol) and piperidine (36 mg, 0.43 mmol) in ethanol (0.2M) was stirred at room temperature for a total of 5 days. The reaction was concentrated to ¼ of its volume and the precipitate was collected by vacuum filtration to give the title compound as a pale orangish-red solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06706709B2
Source datasetuspto-grants-2004_03
ORD IDord-04e993e7259643b294fbed62d7615853
Source noteuspto-grants-2004_03