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HRID491280

反应详情

EQUATION

反应方程式

HRID 491280 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)OC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OCC(Cl)(Cl)Cl
HCID10907393

未命名化合物

PRODUCTS

生成物

1
结构：O=C(N[C@@H](CO)C(=O)OCC(Cl)(Cl)Cl)OCC1c2ccccc2-c2ccccc21
HCID10939458

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O.O=C(O)C(F)(F)F
溶剂HCID22392675

未命名化合物

PROCEDURE

实验过程

Fmoc-Ser(tBu)-OTce was dissolved in TFA-H2O (19:1, 10 mL) and allowed to stir for 5 h. The reaction mixture was concentrated in vacuo and purified by flash chromatography (EtOAc-Hexane, 3:7) to give Fmoc-Ser-OTce (0.83 g, 1.8 mmol, 69% overall yield for the two steps).

WORKUP

后处理

  1. concentrationThe reaction mixture was concentrated in vacuo
  2. custompurified by flash chromatography (EtOAc-Hexane, 3:7)