Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, compound

HRID 491284Notes

Reaction equation

HRID 491284 reaction equation
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Product 1

HCID 21925070HCID 21925070, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture vas concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

Workup

  1. concentrationthe reaction mixture vas concentrated to dryness
  2. customthe residue was dried in vacuo

Sources & evidence

ORD record
ord-87a38af366f242c18772660cac523008
Source dataset
uspto-grants-2009_05
Patent number
US07531526B2

Reaction notes

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