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HRID491428

反应详情

EQUATION

反应方程式

HRID 491428 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1
HCID87949

p-Anisyldithiophosphonic anhydride

C14H14O2P2S4

结构：CC(C)(C)c1ccc(C(=O)Nc2cccc(Br)c2Br)cc1
HCID57678294

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)c1ccc(C(=S)Nc2cccc(Br)c2Br)cc1
HCID57678308

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

The thioamide was prepared according to Example 19 using the 4-tert-butyl-N-(2,3-dibromophenyl)benzamide of Example 22, and Lawesson's reagent in toluene. MS (ESI) m/z 426; HPLC Method B, purity 96.3% at 210-370 nm, 11.4 min.; 98.3% at 262 nm, 11.4 min.; HRMS: calcd for C17H17Br2NS+H+, 425.95212; found (ESI, [M+H]+), 425.9527.

WORKUP

后处理

  1. customat 210-370 nm, 11.4 min.
  2. customat 262 nm, 11.4 min.