HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 8-(Methylsulfonyl)-2,8-diazaspiro[4.5]decane hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2,8-Diazaspiro[4.5]decane-2-carboxylic acid, 8-(methylsulfonyl)-, 1,1-dimethylethyl ester | HCID 66662714 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 8-(Methylsulfonyl)-2,8-diazaspiro[4.5]decane hydrochloride | HCID 17973614 | — |
Reaction Steps
To a solution of 8-methanesulfonyl-2,8-diaza-spiro[4.5]decane-2-carboxylic acid tert-butyl ester (1.32 g) in ethyl acetate (10 ml), a 1 M ethyl acetate solution of HCl (20 ml). After stirring for 2 h at room temperature, solvent is evaporated down to give 8-methanesulfonyl-2,8-diaza-spiro[4.5]decane hydrochloride as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07531546B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-f381f29da1b04360a20fc8de696f5d2b |
| Source note | uspto-grants-2009_05 |