Methyl iodide → HCID 86602241, compound

Participants

Reaction Steps

Trans-3-[4-(dimethylamino)cyclohexylcarbonylamino]-N-(4-chlorophenyl)benzofuran-2-carboxamide (106 mg) obtained in Example 308 is dissolved in dichloromethane (5 ml), and thereto is added methyl iodide (30 μl), and the mixture is stirred at room temperature for 5 hours. To the reaction solution is poured dichloromethane diethyl ether (1/5, 25 ml), and the precipitates are collected by filtration to give the title compound (126 mg).

Provenance & Evidence