Hydrochloric Acid → HCID 67023471, compound

Participants

Reaction Steps

3-Benzyloxy-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid methyl ester (0.6 g, 1.86 mmol) was dissolved in dichloromethane and then added slowly into a mixture of hydrochloric acid in isopropyl alcohol ([5M], 3 mL). The reaction mixture was stirred for 2 hours at room temperature. The solvent was then evaporated and the residue was kept on high vacuum atmosphere overnight to yield a crude product as an oil. The crude product was stored in the freezer as an oil.

Provenance & Evidence