Methylamine → 4-(Methylamino)cyclohexanecarbonitrile

HRID 491898Notes

Reaction equation

[CH3:1][NH2:2].O=[C:4]1[CH2:9][CH2:8][CH:7]([C:10]#[N:11])[CH2:6][CH2:5]1>>[CH3:1][NH:2][CH:4]1[CH2:9][CH2:8][CH:7]([C:10]#[N:11])[CH2:6][CH2:5]1

Participants

Reactant 2

HCID 6329Methylamine

HCID 122356394-Oxocyclohexane-1-carbonitrile

Product 1

HCID 574826414-(Methylamino)cyclohexanecarbonitrile

Procedure

Following the procedure as described in Example 25, STEP D, methyl amine and 4-oxo-cyclohexanecarbonitrile were reacted to yield 4-methyamino-cyclohexanecarbonitrile as a white solid, as its corresponding hydrochloride salt.

Workup

customwere reacted

Sources & evidence

ORD record: ord-67db86910d414809ac6e9a5095d3e038
Source dataset: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07531545B2

Reaction notes

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