反应详情

To a solution of 3-[benzyl-(1-phenyl-ethyl)-amino]-3-cyclohexyl-propionic acid tert-butyl ester (13.7 g, 32.5 mmol) in dichloromethane (65 mL) at 0° C., trifluoroacetic acid (65 mL) was slowly added (over 30 min). The reaction mixture was then stirred for 2 hours at room temperature. The solvent was evaporated and the residue azeotroped (3×50 ml, toluene) to yield a residue.

1. customThe solvent was evaporated
2. customthe residue azeotroped (3×50 ml, toluene)
3. customto yield a residue