Hydrochloric Acid → ethyl 2-((N-methylsulfamoyl)amino)acetate

HRID 492015Notes

Reaction equation

HRID 492015 reaction equation
Cl.C(O[C:7]([N:9](C)[S:10]([NH:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])(=[O:12])=[O:11])=O)CCC>CO>[CH3:7][NH:9][S:10]([NH:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])(=[O:12])=[O:11]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 18449912ethyl 2-((N-(butyloxycarbonyl)-N-methylsulfamoyl)amino)acetate

Product 1

HCID 18449915ethyl 2-((N-methylsulfamoyl)amino)acetate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of HCl in methanol (2 M) is added ethyl 2-((N-(butyloxycarbonyl)-N-methylsulfamoyl)amino)acetate from the previous step (5.0 mmol) in portions at RT and the mixture is stirred for 3 h. After the solvent is removed in vacuo, the residue is washed with diethyl ether to afford ethyl 2-((N-methylsulfamoyl)amino)acetate

Workup

  1. customAfter the solvent is removed in vacuo
  2. washthe residue is washed with diethyl ether

Sources & evidence

ORD record
ord-d5956ee78a6b461c8d6958ffa0bf75da
Source dataset
uspto-grants-2009_05
Patent number
US07531566B2

Reaction notes

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