1-Bromo-2-Chloroethane → 1-(2-Chloroethyl)-4-methylpiperazine hydrochloride

HRID 492024Notes

Reaction equation

[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.Br[CH2:9][CH2:10][Cl:11]>>[ClH:11].[Cl:11][CH2:10][CH2:9][N:5]1[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]1

Participants

Reactant 2

HCID 78491-Bromo-2-Chloroethane

HCID 531671-Methylpiperazine

Product 1

HCID 221271121-(2-Chloroethyl)-4-methylpiperazine hydrochloride

Procedure

N-methyl piperazine and 1-bromo-2-chloroethane are reacted using the procedure for Example OO to afford 1-(2-chloroethyl)-4-methylpiperazine hydrochloride.

Sources & evidence

ORD record: ord-36ed772667a6458e9251e54a21f5ff84
Source dataset: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07531566B2

Reaction notes

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