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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 492030Generated: October 30, 2026

1-Bromo-3-chloropropane → 1-(3-Chloropropyl)-4-(trifluoromethyl)piperidin-4-ol

https://huagongshe.com/reaction/492030

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-chloropropaneHCID 8006—
Reactant4-(Trifluoromethyl)-4-piperidinolHCID 17951321—
Product1-(3-Chloropropyl)-4-(trifluoromethyl)piperidin-4-olHCID 18449831—

Reaction Steps

A solution of 4-(trifluoromethyl)piperidin-4-ol and 1-bromo-3-chloropropane are reacted using the procedure for Example OO to afford 1-(3-chloropropyl)-4-(trifluoromethyl)piperidin-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07531566B2
Source datasetuspto-grants-2009_05
ORD IDord-d534f5a4cf2444f8a17ddd43d6538c31
Source noteuspto-grants-2009_05