Triethylamine → HCID 66593775, compound

HRID 492099Notes

Reaction equation

HRID 492099 reaction equation
[CH3:1][C:2]1[CH2:6][CH:5]=[C:4]([CH3:7])[C:3]=1[C:8]1[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[CH:10][C:9]=1[NH2:16].C(N(CC)CC)C.[C:24](Cl)(=[O:29])[C:25]([CH3:28])([CH3:27])[CH3:26]>>[CH3:7][C:4]1[CH2:5][CH:6]=[C:2]([CH3:1])[C:3]=1[C:8]1[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[CH:10][C:9]=1[NH:16][C:24](=[O:29])[C:25]([CH3:28])([CH3:27])[CH3:26]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 62493Pivaloyl chlorideHCID 665934842-(2,5-Dimethylcyclopenta-1,4-dien-1-yl)-3,5-dimethylaniline

Product 1

HCID 66593775HCID 66593775, compoundYield 70%

Procedure

0.717 g (3.36 mmol) of 2-(2,5-dimethylcyclopenta-1,4-dienyl)-3,5-dimethylphenylamine, 0.408 g (4.03 mmol) of triethylamine, and 0.486 g (4.03 mmol) of pivaloyl chloride were used in the same manner as in Example 11. The resultant reaction product was purified using a column chromatography using a toluene/MC (v/v, 1:1) solvent, and then the solvent in the purified product was removed in vacuum, thereby obtaining while solid (0.698 g, 70%).

Workup

  1. customThe resultant reaction product
  2. customwas purified
  3. customthe solvent in the purified product was removed in vacuum

Sources & evidence

ORD record
ord-6f5772476459428f9bdc4dbda33dfd9b
Source dataset
uspto-grants-2009_05
Patent number
US07531608B2

Reaction notes

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