HCID 178418675, compound → 3-Oxabicyclo[3.2.2]nonane-2,4-dione

HRID 4923Notes

Reaction equation

HRID 4923 reaction equation
[C@H:1]1([C:10]([OH:12])=[O:11])[CH2:6][CH2:5][C@@H:4]([C:7]([OH:9])=O)[CH2:3][CH2:2]1>C(OC(=O)C)(=O)C>[CH:1]12[CH2:2][CH2:3][CH:4]([CH2:5][CH2:6]1)[C:7](=[O:9])[O:12][C:10]2=[O:11]

Participants

3

Reactant 1

HCID 178418675HCID 178418675, compound

Product 1

HCID 140971693-Oxabicyclo[3.2.2]nonane-2,4-dioneYield 97%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

A solution of 2.9 g of cis-cyclohexane-1,4-dicarboxylic acid in 25 ml of acetic anhydride was heated under reflux for 2.5 hours. The solvent was removed by evaporation in vacuo, and the residue was triturated under diethyl ether several times. The residue was dried under high vacuum to give 2.5 g (97% yield) of the title compound.

Workup

  1. temperatureunder reflux for 2.5 hours
  2. customThe solvent was removed by evaporation in vacuo
  3. customthe residue was triturated under diethyl ether several times
  4. customThe residue was dried under high vacuum

Sources & evidence

ORD record
ord-9551d7b99ad4419ca95993482a6ed9e7
Source dataset
uspto-grants-1993_09
Patent number
US05242911

Reaction notes

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